🍩 Database of Original & Non-Theoretical Uses of Topology
(found 3 matches in 0.001517s)
The Persistent Homology Mathematical Framework Provides Enhanced Genotype-to-Phenotype Associations for Plant Morphology (2018)Mao Li, Margaret H. Frank, Viktoriya Coneva, Washington Mio, Daniel H. Chitwood, Christopher N. Topp
AbstractEfforts to understand the genetic and environmental conditioning of plant morphology are hindered by the lack of flexible and effective tools for quantifying morphology. Here, we demonstrate that persistent-homology-based topological methods can improve measurement of variation in leaf shape, serrations, and root architecture. We apply these methods to 2D images of leaves and root systems in field-grown plants of a domesticated introgression line population of tomato (Solanum pennellii). We find that compared with some commonly used conventional traits, (1) persistent-homology-based methods can more comprehensively capture morphological variation; (2) these techniques discriminate between genotypes with a larger normalized effect size and detect a greater number of unique quantitative trait loci (QTLs); (3) multivariate traits, whether statistically derived from univariate or persistent-homology-based traits, improve our ability to understand the genetic basis of phenotype; and (4) persistent-homology-based techniques detect unique QTLs compared to conventional traits or their multivariate derivatives, indicating that previously unmeasured aspects of morphology are now detectable. The QTL results further imply that genetic contributions to morphology can affect both the shoot and root, revealing a pleiotropic basis to natural variation in tomato. Persistent homology is a versatile framework to quantify plant morphology and developmental processes that complements and extends existing methods.
Computing Robustness and Persistence for Images (2010)P. Bendich, H. Edelsbrunner, M. Kerber
AbstractWe are interested in 3-dimensional images given as arrays of voxels with intensity values. Extending these values to a continuous function, we study the robustness of homology classes in its level and interlevel sets, that is, the amount of perturbation needed to destroy these classes. The structure of the homology classes and their robustness, over all level and interlevel sets, can be visualized by a triangular diagram of dots obtained by computing the extended persistence of the function. We give a fast hierarchical algorithm using the dual complexes of oct-tree approximations of the function. In addition, we show that for balanced oct-trees, the dual complexes are geometrically realized in R3 and can thus be used to construct level and interlevel sets. We apply these tools to study 3-dimensional images of plant root systems.