🍩 Database of Original & Non-Theoretical Uses of Topology
(found 4 matches in 0.000895s)
The Importance of Forgetting: Limiting Memory Improves Recovery of Topological Characteristics From Neural Data (2018)Samir Chowdhury, Bowen Dai, Facundo Mémoli
AbstractWe develop of a line of work initiated by Curto and Itskov towards understanding the amount of information contained in the spike trains of hippocampal place cells via topology considerations. Previously, it was established that simply knowing which groups of place cells fire together in an animal’s hippocampus is sufficient to extract the global topology of the animal’s physical environment. We model a system where collections of place cells group and ungroup according to short-term plasticity rules. In particular, we obtain the surprising result that in experiments with spurious firing, the accuracy of the extracted topological information decreases with the persistence (beyond a certain regime) of the cell groups. This suggests that synaptic transience, or forgetting, is a mechanism by which the brain counteracts the effects of spurious place cell activity.
Measurement of the Topological Dimension of Hippocampal Place Cell Activity (2018)Steven E. Fox, James B. Ranck
Reconceiving the Hippocampal Map as a Topological Template (2014)Yuri Dabaghian, Vicky L. Brandt, Loren M. Frank
AbstractThe role of the hippocampus in spatial cognition is incontrovertible yet controversial. Place cells, initially thought to be location-specifiers, turn out to respond promiscuously to a wide range of stimuli. Here we test the idea, which we have recently demonstrated in a computational model, that the hippocampal place cells may ultimately be interested in a space's topological qualities (its connectivity) more than its geometry (distances and angles); such higher-order functioning would be more consistent with other known hippocampal functions. We recorded place cell activity in rats exploring morphing linear tracks that allowed us to dissociate the geometry of the track from its topology. The resulting place fields preserved the relative sequence of places visited along the track but did not vary with the metrical features of the track or the direction of the rat's movement. These results suggest a reinterpretation of previous studies and new directions for future experiments.