🍩 Database of Original & NonTheoretical Uses of Topology
(found 8 matches in 0.002324s)


Raman Spectroscopy and Topological Machine Learning for Cancer Grading (2023)
Francesco Conti, Mario D’Acunto, Claudia Caudai, Sara Colantonio, Raffaele Gaeta, Davide Moroni, Maria Antonietta PascaliAbstract
In the last decade, Raman Spectroscopy is establishing itself as a highly promising technique for the classification of tumour tissues as it allows to obtain the biochemical maps of the tissues under investigation, making it possible to observe changes among different tissues in terms of biochemical constituents (proteins, lipid structures, DNA, vitamins, and so on). In this paper, we aim to show that techniques emerging from the crossfertilization of persistent homology and machine learning can support the classification of Raman spectra extracted from cancerous tissues for tumour grading. In more detail, topological features of Raman spectra and machine learning classifiers are trained in combination as an automatic classification pipeline in order to select the bestperforming pair. The case study is the grading of chondrosarcoma in four classes: cross and leaveonepatientout validations have been used to assess the classification accuracy of the method. The binary classification achieves a validation accuracy of 81% and a test accuracy of 90%. Moreover, the test dataset has been collected at a different time and with different equipment. Such results are achieved by a support vector classifier trained with the Betti Curve representation of the topological features extracted from the Raman spectra, and are excellent compared with the existing literature. The added value of such results is that the model for the prediction of the chondrosarcoma grading could easily be implemented in clinical practice, possibly integrated into the acquisition system. 
Topology in Cyber Research (2022)
Steve Huntsman, Jimmy Palladino, Michael RobinsonAbstract
We give an idiosyncratic overview of applications of topology to cyber research, spanning the analysis of variables/assignments and control flow in computer programs, a brief sketch of topological data analysis in one dimension, and the use of sheaves to analyze wireless networks. The text is from a chapter in the forthcoming book Mathematics in Cyber Research, to be published by Taylor and Francis. 
Severe Slugging Flow Identification From Topological Indicators (2022)
Simone CasoloAbstract
In this work, topological data analysis is used to identify the onset of severe slug flow in offshore petroleum production systems. Severe slugging is a multiphase flow regime known to be very inefficient and potentially harmful to process equipment and it is characterized by large oscillations in the production fluid pressure. Time series from pressure sensors in subsea oil wells are processed by means of Takens embedding to produce point clouds of data. Embedded sensor data is then analyzed using persistent homology to obtain topological indicators capable of revealing the occurrence of severe slugging in a conditionbased monitoring approach. A large dataset of well events consisting of both real and simulated data is used to demonstrate the possibilty of authomatizing severe slugging detection from live data via topological data analysis. Methods based on persistence diagrams are shown to accurately identify severe slugging and to classify different flow regimes from pressure signals of producing wells with supervised machine learning. 
Topological Data Analysis: Concepts, Computation, and Applications in Chemical Engineering (2021)
Alexander D. Smith, Paweł Dłotko, Victor M. ZavalaAbstract
A primary hypothesis that drives scientific and engineering studies is that data has structure. The dominant paradigms for describing such structure are statistics (e.g., moments, correlation functions) and signal processing (e.g., convolutional neural nets, Fourier series). Topological Data Analysis (TDA) is a field of mathematics that analyzes data from a fundamentally different perspective. TDA represents datasets as geometric objects and provides dimensionality reduction techniques that project such objects onto lowdimensional descriptors. The key properties of these descriptors (also known as topological features) are that they provide multiscale information and that they are stable under perturbations (e.g., noise, translation, and rotation). In this work, we review the key mathematical concepts and methods of TDA and present different applications in chemical engineering. 
The Euler Characteristic: A General Topological Descriptor for Complex Data (2021)
Alexander Smith, Victor ZavalaAbstract
Datasets are mathematical objects (e.g., point clouds, matrices, graphs, images, fields/functions) that have shape. This shape encodes important knowledge about the system under study. Topology is an area of mathematics that provides diverse tools to characterize the shape of data objects. In this work, we study a specific tool known as the Euler characteristic (EC). The EC is a general, lowdimensional, and interpretable descriptor of topological spaces defined by data objects. We revise the mathematical foundations of the EC and highlight its connections with statistics, linear algebra, field theory, and graph theory. We discuss advantages offered by the use of the EC in the characterization of complex datasets; to do so, we illustrate its use in different applications of interest in chemical engineering such as process monitoring, flow cytometry, and microscopy. We show that the EC provides a descriptor that effectively reduces complex datasets and that this reduction facilitates tasks such as visualization, regression, classification, and clustering. 
Topology of Frame Field Meshing (2020)
Piotr BebenAbstract
In the past decade frame fields have emerged as a promising approach for generating hexahedral meshes for CFD and CAE applications. One important problem asks for construction of a boundary aligned frame field with prescribed singularity constraints that correspond to a valid hexahedral mesh. We give a necessary and sufficient condition in terms of solutions to a system of monomial equations whose variables are in the binary octahedral group. Along the way we look at frame field design from an algebraic topological perspective, proving various results, some known, some new. 
Topological Differential Testing (2020)
Kristopher Ambrose, Steve Huntsman, Michael Robinson, Matvey YutinAbstract
We introduce topological differential testing (TDT), an approach to extracting the consensus behavior of a set of programs on a corpus of inputs. TDT uses the topological notion of a simplicial complex (and implicitly draws on richer topological notions such as sheaves and persistence) to determine inputs that cause inconsistent behavior and in turn reveal \emph\de facto\ input specifications. We gently introduce TDT with a toy example before detailing its application to understanding the PDF file format from the behavior of various parsers. Finally, we discuss theoretical details and other possible applications.