🍩 Database of Original & Non-Theoretical Uses of Topology

1. Acridine Derivatives as Inhibitors of the IRE1α–XBP1 Pathway Are Cytotoxic to Human Multiple Myeloma (2016)

   Dadi Jiang, Arvin B. Tam, Muthuraman Alagappan, Michael P. Hay, Aparna Gupta, Margaret M. Kozak, David E. Solow-Cordero, Pek Y. Lum, Nicholas C. Denko, Amato J. Giaccia

   • Export citation

   • Acridine derivatives
   • Drug discovery
   • Multiple myeloma
   • Unfolded protein
   • Innovate
   • Mapper

2. A Multimodal Data Analysis Approach for Targeted Drug Discovery Involving Topological Data Analysis (TDA) (2016)

   Muthuraman Alagappan, Dadi Jiang, Nicholas Denko, Albert C. Koong

   • Export citation

   • Drug
   • Medicine
   • Clustering
   • Mapper

3. Integrative Methods for Analyzing Big Data in Precision Medicine (2016)

   Vladimir Gligorijević, Noël Malod-Dognin, Nataša Pržulj

   • Export citation

   • Bioinformatics
   • Biomarkers discovery
   • Disease subtyping
   • Drug repurposing
   • Integration methods
   • Medicine
   • Personalized medicine
   • Mapper

4. ToDD: Topological Compound Fingerprinting in Computer-Aided Drug Discovery (2022)

   Andaç Demir, Baris Coskunuzer, Yulia Gel, Ignacio Segovia-Dominguez, Yuzhou Chen, Bulent Kiziltan

   Community Resources

   • Data
   • Video

   • URL
   • Export citation

   • Bioinformatics
   • medicine
   • medicine:drug
   • Graphs
   • Graphs:compound
   • Graphs:molecule
   • Persistent homology
   • Persistent homology:betti numbers